CHEMBL1222624


SMILES CC1CN(C2=Cc3ccccc3Cn3ccnc32)CC(C)N1CCC(=O)O
InChIKey ZXFALDNPMLUADA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 7.7 7.7 7.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database