CHEMBL1223750


SMILES FC(F)(F)c1cccc(N2CCN(CCCCNc3nccc4ccccc34)CC2)c1
InChIKey KFWSEMIBLPIBOC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 7.17 7.17 7.17 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.24 8.12 9.0 ChEMBL
H4 HRH4 Human Histamine A pKi 8.27 8.27 8.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database