CHEMBL1224527


SMILES Oc1ccc2c(c1O)C[C@@H](c1ccccc1)[C@@H]1CCNC[C@@H]21
InChIKey FKYWSGYMKJUZEP-ZOBUZTSGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 1
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 5.19 5.19 5.19 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.96 5.96 5.96 ChEMBL
D1 DRD1 Human Dopamine A pKi 4.75 6.04 7.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.64 6.64 6.64 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.46 5.46 5.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pEC50 9.19 9.19 9.19 ChEMBL