Macimorelin


SMILES O=CN[C@@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](NC(=O)C(N)(C)C)Cc1c[nH]c2c1cccc2
InChIKey UJVDJAPJQWZRFR-DHIUTWEWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 6
Rotatable bonds 10
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ghrelin GHSR Human Ghrelin A pIC50 7.81 7.81 7.81 Guide to Pharmacology
ghrelin GHSR Human Ghrelin A pIC50 6.91 7.28 7.64 ChEMBL
ghrelin GHSR Human Ghrelin A pIC50 7.11 7.11 7.11 Drug Central