levallorphan


SMILES C=CCN1CC[C@@]23[C@H]([C@H]1Cc1c3cc(cc1)O)CCCC2
InChIKey OZYUPQUCAUTOBP-QXAKKESOSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 283.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.77 8.99 9.32 ChEMBL
μ OPRM Rat Opioid A pKi 8.7 9.12 9.67 PDSP Ki database
δ OPRD Rat Opioid A pKi 8.66 8.66 8.66 PDSP Ki database
μ OPRM Human Opioid A pKi 8.03 8.03 8.03 Drug Central
μ OPRM Human Opioid A pKi 8.77 9.05 9.32 Guide to Pharmacology
κ OPRK Rat Opioid A pKi 5.96 5.96 5.96 PDSP Ki database
μ OPRM Mouse Opioid A pKi 9.01 9.02 9.02 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 9.2 9.2 9.2 ChEMBL
μ OPRM Rat Opioid A pIC50 8.04 8.04 8.04 Drug Central