L-serine-O-phosphate


SMILES OC(=O)[C@H](COP(=O)(O)O)N
InChIKey BZQFBWGGLXLEPQ-REOHCLBHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 185.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Endogenous
Approved drug Yes

Database connections

Structure pdb 7E9H

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu7 GRM7 Human Metabotropic glutamate C pKi 4.4 4.4 4.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 8.22 8.22 8.22 Drug Central
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 8.19 8.19 8.19 Drug Central
mGlu7 GRM7 Human Metabotropic glutamate C pEC50 8.35 8.35 8.35 Drug Central
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 5.89 5.95 6.0 ChEMBL
mGlu4 GRM4 Human Metabotropic glutamate C pEC50 5.9 5.9 5.9 Guide to Pharmacology
mGlu6 GRM6 Human Metabotropic glutamate C pEC50 6.4 6.4 6.4 Guide to Pharmacology
mGlu7 GRM7 Human Metabotropic glutamate C pEC50 4.5 4.5 4.5 Guide to Pharmacology
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 8.14 8.14 8.14 Drug Central
mGlu8 GRM8 Human Metabotropic glutamate C pIC50 6.2 6.7 7.2 Guide to Pharmacology
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 8.25 8.25 8.25 Drug Central
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 5.57 5.57 5.57 ChEMBL
mGlu4 GRM4 Rat Metabotropic glutamate C pEC50 8.27 8.27 8.27 Drug Central
mGlu4 GRM4 Rat Metabotropic glutamate C pEC50 5.4 5.4 5.4 ChEMBL
mGlu4 GRM4 Rat Metabotropic glutamate C pIC50 5.4 5.8 6.2 Guide to Pharmacology