CHEMBL1255588


SMILES CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc(c43)[C@H]2C1
InChIKey ZZJYIKPMDIWRSN-TZBSWOFLSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 361.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 8.74 8.74 8.74 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.44 8.95 9.52 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.73 6.73 6.73 ChEMBL
D1 DRD1 Human Dopamine A pKi 8.55 8.55 8.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.19 8.8 9.37 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.54 9.04 9.43 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.53 8.53 8.53 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 7.92 7.92 7.92 ChEMBL
D3 DRD3 Human Dopamine A pIC50 8.0 8.46 8.92 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.82 8.23 8.85 ChEMBL