CHEMBL1257688


SMILES O=C(CCCN1CCC(O)(c2cc3ccc2CCc2ccc(cc2)CC3)CC1)c1ccc(F)cc1
InChIKey ZXZSMMMPXXEGFH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 471.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.14 9.14 9.14 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.32 8.38 8.44 ChEMBL
D1 DRD1 Pig Dopamine A pKi 7.0 7.0 7.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database