CHEMBL1259173


SMILES CC(=O)NCc1ccc2c(c1)[C@H](N1CCN(C)CC1)Cc1ccccc1S2
InChIKey YBCFDDCJLZVHPZ-HXUWFJFHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 9.05 9.05 9.05 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.38 9.38 9.38 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 8.82 8.82 8.82 ChEMBL
H1 HRH1 Human Histamine A pKi 8.44 8.44 8.44 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.51 8.51 8.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.57 7.57 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database