CHEMBL1259174


SMILES CC(=O)NCc1ccc2c(c1)[C@@H](N1CCN(C)CC1)Cc1ccccc1S2
InChIKey YBCFDDCJLZVHPZ-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 381.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 9.38 9.38 9.38 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.47 9.47 9.47 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 9.01 9.01 9.01 ChEMBL
H1 HRH1 Human Histamine A pKi 8.6 8.6 8.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.58 7.58 7.58 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.48 8.48 8.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database