CHEMBL1259189


SMILES CC(C)C(=O)NCc1ccc2c(c1)[C@H](N1CCN(C)CC1)Cc1ccccc1S2
InChIKey SHVCHMGRIYXVAY-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Golden hamster Adrenoceptors A pKi 9.57 9.57 9.57 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.37 9.37 9.37 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKi 9.19 9.19 9.19 ChEMBL
H1 HRH1 Human Histamine A pKi 8.35 8.35 8.35 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.1 8.1 8.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database