SB-258741


SMILES Cc1cccc(S(=O)(=O)N2CCC[C@@H]2CCN2CCC(C)CC2)c1
InChIKey YVWGGGGMRDLOGA-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.5 8.51 8.52 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.49 8.5 8.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database