PIPERTRAMINE


SMILES COc1ccccc1CN1CCC(C2CCN(CCCCCCCCN3CCC(C4CCN(Cc5ccccc5OC)CC4)CC3)CC2)CC1
InChIKey HECAWZFPXYNICY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 17
Molecular weight (Da) 686.6

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.98 6.98 6.98 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.82 7.82 7.82 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 6.38 6.38 6.38 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.07 8.07 8.07 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.7 7.7 7.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database