CHEMBL1276220


SMILES C[C@H](Oc1ccccc1C1CC1)C1=NCCN1
InChIKey QYCJTZDZQXSXSC-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.58 6.58 6.58 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.2 7.2 7.2 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.68 7.68 7.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.5 5.5 5.5 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.45 7.45 7.45 ChEMBL