CHEMBL1276248


SMILES C[C@H](Oc1ccccc1-c1ccsc1)C1=NCCN1
InChIKey IAIZHDGEGFGNMO-NSHDSACASA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 272.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.35 6.35 6.35 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.9 6.9 6.9 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.35 7.35 7.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.0 6.0 6.0 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 8.2 8.2 8.2 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.2 7.2 7.2 ChEMBL