CHEMBL1277312


SMILES O=C(O)C1CN(C2CCC3(Cc4ccccc4Oc4ccccc43)C2)C1
InChIKey IRGGYSVFJCBILG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 7.85 7.85 7.85 ChEMBL
H1 HRH1 Human Histamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database