CHEMBL1277679


SMILES O=C(O)C1(O)CCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)CC1
InChIKey IYAJUPFWKMPDJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.6 6.6 6.6 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database