CHEMBL1278088


SMILES Nn1c(CCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2c(c1=O)CCCC2
InChIKey WFQOETMVYMINSA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 432.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.15 9.15 9.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 6.0 6.0 6.0 ChEMBL
H1 HRH1 Human Histamine A pIC50 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.65 7.65 7.65 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 8.85 8.85 8.85 ChEMBL