ML 10375


SMILES COc1cc(N)c(cc1C(=O)OCCN1CC(C)CC(C1)C)Cl
InChIKey BUEFUOFMOXJXAR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT4

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.8 9.4 10.0 Guide to Pharmacology
5-HT4 5HT4R Rat 5-Hydroxytryptamine A pKi 8.63 9.11 9.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database