MT-II
SMILES | None |
InChIKey | JDKLPDJLXHXHNV-MFVUMRCOSA-N |
Sequence | XDHFRWK |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MC3 | MC3R | Human | Melanocortin | A | pKi | 8.3 | 8.3 | 8.3 | Guide to Pharmacology |
MC4 | MC4R | Human | Melanocortin | A | pKi | 8.2 | 8.5 | 8.8 | Guide to Pharmacology |
MC1 | MSHR | Human | Melanocortin | A | pKi | 9.88 | 9.9 | 9.95 | ChEMBL |
MC3 | MC3R | Human | Melanocortin | A | pKi | 7.73 | 8.01 | 8.4 | ChEMBL |
MC4 | MC4R | Human | Melanocortin | A | pKi | 8.9 | 9.08 | 9.34 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MC1 | MSHR | Human | Melanocortin | A | pIC50 | 9.4 | 9.4 | 9.4 | Guide to Pharmacology |
MC5 | MC5R | Human | Melanocortin | A | pIC50 | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
MC5 | MC5R | Mouse | Melanocortin | A | pEC50 | 9.24 | 9.75 | 10.17 | ChEMBL |
MC1 | MSHR | Mouse | Melanocortin | A | pEC50 | 9.66 | 10.49 | 10.7 | ChEMBL |
MC3 | MC3R | Mouse | Melanocortin | A | pEC50 | 9.46 | 9.74 | 9.89 | ChEMBL |
MC4 | MC4R | Mouse | Melanocortin | A | pEC50 | 10.06 | 10.22 | 10.4 | ChEMBL |
MC1 | MSHR | Human | Melanocortin | A | pEC50 | 6.96 | 9.19 | 10.0 | ChEMBL |
MC1 | MSHR | Human | Melanocortin | A | pIC50 | 8.17 | 9.22 | 10.0 | ChEMBL |
MC5 | MC5R | Human | Melanocortin | A | pEC50 | 7.47 | 8.31 | 8.83 | ChEMBL |
MC5 | MC5R | Human | Melanocortin | A | pIC50 | 7.36 | 8.07 | 8.82 | ChEMBL |
MC3 | MC3R | Human | Melanocortin | A | pEC50 | 7.47 | 8.72 | 10.21 | ChEMBL |
MC3 | MC3R | Human | Melanocortin | A | pIC50 | 8.01 | 8.63 | 8.92 | ChEMBL |
MC4 | MC4R | Human | Melanocortin | A | pIC50 | 8.13 | 8.8 | 9.14 | ChEMBL |
MC4 | MC4R | Human | Melanocortin | A | pEC50 | 8.0 | 8.85 | 10.4 | ChEMBL |