nalorphine


SMILES C=CCN1CC[C@@]23[C@@H]4[C@H]1Cc1c3c(O[C@H]2[C@H](C=C4)O)c(cc1)O
InChIKey UIQMVEYFGZJHCZ-SSTWWWIQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.4 7.4 7.4 Guide to Pharmacology
κ OPRK Human Opioid A pKi 7.9 8.5 9.1 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.9 8.9 8.9 Guide to Pharmacology
μ OPRM Rat Opioid A pKi 8.19 8.45 8.7 ChEMBL
δ OPRD Human Opioid A pKi 6.92 6.92 6.92 ChEMBL
κ OPRK Human Opioid A pKi 8.7 9.06 9.42 ChEMBL
μ OPRM Human Opioid A pKi 9.44 9.58 9.72 ChEMBL
δ OPRD Human Opioid A pKi 8.16 8.16 8.16 Drug Central
κ OPRK Human Opioid A pKi 8.03 8.03 8.03 Drug Central
μ OPRM Human Opioid A pKi 8.01 8.01 8.01 Drug Central
κ OPRK Guinea pig Opioid A pKi 8.11 8.11 8.11 Drug Central
μ OPRM Rat Opioid A pKi 8.06 8.06 8.06 Drug Central
κ OPRK Guinea pig Opioid A pKi 7.82 7.82 7.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database