naphazoline


SMILES C1CN=C(N1)Cc1cccc2c1cccc2
InChIKey CNIIGCLFLJGOGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 210.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.5 6.5 6.5 Guide to Pharmacology
α2A ADA2A Human Adrenoceptors A pKi 8.11 8.11 8.11 Drug Central
α2A ADA2A Human Adrenoceptors A pKi 7.68 7.68 7.68 PDSP Ki database
α2A ADA2A Human Adrenoceptors A pKi 7.0 7.0 7.0 Guide to Pharmacology
α2B ADA2B Human Adrenoceptors A pKi 8.19 8.19 8.19 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 6.39 6.39 6.39 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.19 8.19 8.19 Drug Central
α2C ADA2C Human Adrenoceptors A pKi 6.39 6.39 6.39 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.64 8.64 8.64 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.4 6.4 6.4 Guide to Pharmacology
α2A ADA2A Mouse Adrenoceptors A pKi 7.77 7.86 7.94 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pEC50 7.2 7.2 7.2 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 6.6 7.75 8.9 Guide to Pharmacology
α2A ADA2A Human Adrenoceptors A pIC50 7.8 7.8 7.8 Guide to Pharmacology
α2C ADA2C Human Adrenoceptors A pEC50 7.26 7.26 7.26 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 7.1 7.1 7.1 Guide to Pharmacology
α2C ADA2C Human Adrenoceptors A pEC50 7.69 7.69 7.69 Guide to Pharmacology
TA1 TAAR1 Human Trace amine A pEC50 6.85 6.85 6.85 ChEMBL
TA1 TAAR1 Human Trace amine A pIC50 5.94 5.94 5.94 ChEMBL