NPY


SMILES None
InChIKey BPGXUIVWLQTVLZ-OFGSCBOVSA-N
Sequence YPSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y1 NPY1R Human Neuropeptide Y A pKi 8.7 8.7 8.7 ChEMBL
Y1 NPY1R Human Neuropeptide Y A pKi 9.7 9.7 9.7 Guide to Pharmacology
Y2 NPY2R Human Neuropeptide Y A pKi 9.52 9.52 9.52 ChEMBL
Y2 NPY2R Human Neuropeptide Y A pKi 9.1 9.2 9.3 Guide to Pharmacology
Y1 NPY1R Rat Neuropeptide Y A pKi 10.0 10.0 10.0 Guide to Pharmacology
Y4 NPY4R Rat Neuropeptide Y A pKi 8.7 8.7 8.7 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y2 Q9ERC0 Rat Neuropeptide Y A pIC50 9.35 9.35 9.35 ChEMBL