CHEMBL1330311
SMILES | Cc1csc(-c2coc3cc(O)cc(C)c3c2=O)n1 |
InChIKey | NQLIVLASGOOYQX-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 1 |
Rotatable bonds | 1 |
Molecular weight (Da) | 273.0 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Ligand site mutations | A2A |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
NPS | NPSR1 | Human | Neuropeptide S | A | Potency | 6.5 | 6.5 | 6.5 | ChEMBL |
OX1 | OX1R | Human | Orexin | A | pIC50 | 4.98 | 5.29 | 5.6 | ChEMBL |