pasireotide


SMILES None
InChIKey VMZMNAABQBOLAK-DBILLSOUSA-N
Sequence XXWKYF

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pKi 8.2 8.2 8.2 ChEMBL
SST2 SSR2 Human Somatostatin A pKi 9.0 9.0 9.0 ChEMBL
SST3 SSR3 Human Somatostatin A pKi 9.1 9.1 9.1 ChEMBL
SST5 SSR5 Human Somatostatin A pKi 9.9 9.9 9.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Human Somatostatin A pIC50 8.0 8.0 8.0 Guide to Pharmacology
SST3 SSR3 Human Somatostatin A pIC50 8.8 8.8 8.8 Guide to Pharmacology
SST5 SSR5 Human Somatostatin A pIC50 9.8 9.8 9.8 Guide to Pharmacology
SST2 SSR2 Rat Somatostatin A pEC50 7.76 7.01 9.07 Guide to Pharmacology
SST2 SSR2 Human Somatostatin A pIC50 9.0 9.0 9.0 Guide to Pharmacology