CHEMBL14022


SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1
InChIKey XEMCUJCVRDSIHH-YFVAEKQCSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 425.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.66 8.66 8.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 6.07 6.07 6.07 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.8 7.8 7.8 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.3 7.3 7.3 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.51 6.51 6.51 ChEMBL