Biased Signaling Atlas

piribedil

SMILES	c1cnc(nc1)N1CCN(CC1)Cc1ccc2c(c1)OCO2
InChIKey	OQDPVLVUJFGPGQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	298.1

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Drug Central DrugBank GPCRdb

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.4	6.4	6.4	Guide to Pharmacology
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.35	6.35	6.35	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	8.19	8.19	8.19	Drug Central
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	5.9	5.9	5.9	Guide to Pharmacology
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	5.92	5.92	5.92	PDSP Ki database
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	8.23	8.23	8.23	Drug Central
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
D₂	DRD2	Human	Dopamine	A	pKi	6.88	6.88	6.88	PDSP Ki database
D₂	DRD2	Rat	Dopamine	A	pKi	6.74	6.74	6.74	PDSP Ki database
D₂	DRD2	Human	Dopamine	A	pKi	8.16	8.16	8.16	Drug Central
D₂	DRD2	Human	Dopamine	A	pKi	6.8	6.85	6.9	Guide to Pharmacology
D₃	DRD3	Human	Dopamine	A	pKi	6.6	6.6	6.6	Guide to Pharmacology
D₃	DRD3	Human	Dopamine	A	pKi	6.63	6.63	6.63	PDSP Ki database
D₃	DRD3	Human	Dopamine	A	pKi	8.18	8.18	8.18	Drug Central
D₄	DRD4	Human	Dopamine	A	pKi	6.5	6.5	6.5	Guide to Pharmacology
D₄	DRD4	Human	Dopamine	A	pKi	6.52	6.52	6.52	PDSP Ki database
D₄	DRD4	Human	Dopamine	A	pKi	8.19	8.19	8.19	Drug Central
D₅	DRD5	Human	Dopamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
H₁	HRH1	Guinea pig	Histamine	A	pKi	5.0	5.0	5.0	PDSP Ki database
α_1A	ADA1A	Human	Adrenoceptors	A	pKi	6.1	6.1	6.1	Guide to Pharmacology
α_1A	ADA1A	Human	Adrenoceptors	A	pKi	8.21	8.21	8.21	Drug Central
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.21	5.21	5.21	PDSP Ki database
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	8.28	8.28	8.28	Drug Central
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	6.09	6.38	6.66	PDSP Ki database
α_1D	ADA1D	Human	Adrenoceptors	A	pKi	8.18	8.18	8.18	Drug Central
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	7.1	7.1	7.1	Guide to Pharmacology
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	7.05	7.05	7.05	PDSP Ki database
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	8.15	8.15	8.15	Drug Central
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	6.54	6.54	6.54	PDSP Ki database
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	8.18	8.18	8.18	Drug Central
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	7.2	7.2	7.2	Guide to Pharmacology
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	7.16	7.16	7.16	PDSP Ki database
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	8.14	8.14	8.14	Drug Central
β₁	ADRB1	Human	Adrenoceptors	A	pKi	5.0	5.0	5.0	PDSP Ki database
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.0	5.0	5.0	PDSP Ki database

Showing 1 to 39 of 39 entries

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	4.85	4.95	5.05	ChEMBL

Showing 1 to 1 of 1 entries

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