quinelorane


SMILES CCCN1CCC[C@H]2[C@H]1Cc1cnc(nc1C2)N
InChIKey TUFADSGTJUOBEH-ZWNOBZJWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 246.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 5.5 5.6 5.7 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 9.03 9.03 9.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.2 7.3 7.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.8 4.8 4.8 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 6.82 6.82 6.82 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.35 7.62 8.7 ChEMBL
D3 DRD3 Human Dopamine A pEC50 9.0 9.0 9.0 ChEMBL