rosiglitazone


SMILES O=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C
InChIKey YASAKCUCGLMORW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 357.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT1 AGTRA Rat Angiotensin A pKi 9.64 9.64 9.64 ChEMBL
AT1 AGTRA Rat Angiotensin A pKi 8.02 8.02 8.02 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pEC50 4.94 4.94 4.94 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pEC50 8.25 8.25 8.25 Drug Central
FFA1 FFAR1 Human Free fatty acid A pEC50 5.6 5.6 5.6 Guide to Pharmacology