MK-8666 [332219]



MK-8666


SMILES Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2cc3c(cn2)[C@H]2[C@@H](C3)[C@@H]2C(=O)O)c1
InChIKey CODQKEMYZZKQAE-QPVYNBJUSA-N

Chemical Properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Log P 4.728
Molecular weight (Da) 521.2
Stereochemistry info partial

Database connections

Structure pdb 5TZR 5TZY

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

MK-8666


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 0
Phase III 0
Phase IV 0

Database connections

Structure pdb 5TZR 5TZY

Compound is not listed as a drug.