RO3244794


SMILES Fc1ccc(cc1)CC(C(=O)O)NC(=O)OCc1cc2c(o1)ccc(c2)c1ccc(cc1)F
InChIKey IDONYPMIPXYFLY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 451.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pKi 6.9 6.9 6.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
IP PI2R Human Prostanoid A pA2 8.5 8.5 8.5 Guide to Pharmacology
IP PI2R Human Prostanoid A pKB 9.1 9.31 9.53 Guide to Pharmacology