BIRIPERONE


SMILES O=C(CCCN1CCN2Cc3[nH]c4ccccc4c3CC2C1)c1ccc(F)cc1
InChIKey YCNCIZWAGQTWBI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 391.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pKi 6.37 6.37 6.37 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.88 7.88 7.88 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.96 7.96 7.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.1 8.1 8.1 Drug Central
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.12 8.12 8.12 Drug Central
D1 DRD1 Rat Dopamine A pKi 8.2 8.2 8.2 Drug Central
D2 DRD2 Rat Dopamine A pKi 8.1 8.1 8.1 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database