CHEMBL143022


SMILES O=C1CC(CN2CCC(C(=O)c3ccc(F)cc3)CC2)Cc2occc21
InChIKey XFBPGUPMMWBWAS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.71 6.71 6.71 ChEMBL
D1 DRD1 Rat Dopamine A pKi 6.71 6.71 6.71 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.02 7.02 7.02 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.81 5.81 5.81 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.02 7.15 7.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database