saralasin
SMILES | None |
InChIKey | PFGWGEPQIUAZME-UHFFFAOYSA-N |
Sequence | XRVYVHPA |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
AT1 | AGTRB | Rat | Angiotensin | A | pKi | 8.77 | 8.77 | 8.77 | PDSP Ki database |
AT1 | AGTR1 | Human | Angiotensin | A | pKi | 8.01 | 8.01 | 8.01 | Drug Central |
AT2 | AGTR2 | Human | Angiotensin | A | pKi | 8.01 | 8.01 | 8.01 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
AT2 | AGTR2 | Rat | Angiotensin | A | pIC50 | 9.0 | 9.0 | 9.0 | Guide to Pharmacology |
AT2 | AGTR2 | Rat | Angiotensin | A | pIC50 | 8.05 | 8.05 | 8.05 | Drug Central |
AT1 | AGTRB | Rat | Angiotensin | A | pIC50 | 8.06 | 8.06 | 8.06 | Drug Central |