TM-38837


SMILES CCc1c(nn(c1c1ccc(s1)C#Cc1ccc(cc1)C(F)(F)F)c1ccc(cc1Cl)Cl)C(=O)NN1CCCCC1
InChIKey VQOCBFYUDSBDCZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 616.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pIC50 8.07 8.07 8.07 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 8.07 8.07 8.07 Guide to Pharmacology
CB2 CNR2 Human Cannabinoid A pIC50 6.22 6.22 6.22 Guide to Pharmacology