CHEMBL140258


SMILES N#Cc1ccc2cc(CN3CCN(c4ccccc4Cl)CC3)[nH]c2c1
InChIKey WZJWRRMYYXEGFD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 350.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.47 8.47 8.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.04 6.04 6.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.3 6.48 6.66 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 5.72 5.72 5.72 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database