TUG-770


SMILES N#CCc1ccccc1C#Cc1ccc(c(c1)F)CCC(=O)O
InChIKey KIZUBVPJNPVIIN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 307.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Human Free fatty acid A pKi 7.07 7.07 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
FFA1 FFAR1 Rat Free fatty acid A pEC50 6.49 6.49 6.49 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pEC50 7.58 7.93 8.23 ChEMBL
FFA1 FFAR1 Human Free fatty acid A pEC50 8.2 8.2 8.2 Guide to Pharmacology
FFA4 FFAR4 Human Free fatty acid A pEC50 6.03 6.03 6.03 ChEMBL
FFA1 FFAR1 Mouse Free fatty acid A pEC50 6.83 6.83 6.83 ChEMBL