U101958


SMILES CC(Oc1cccnc1N(C1CCN(CC1)Cc1ccccc1)C)C
InChIKey WFLHEXUTTRRXFJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 339.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.9 8.9 8.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 8.1 8.2 8.3 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.21 6.21 6.21 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.26 5.26 5.26 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.8 4.8 4.8 ChEMBL