CLEMIZOLE


SMILES Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc32)cc1
InChIKey CJXAEXPPLWQRFR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 325.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 8.19 8.19 8.19 Drug Central
H4 HRH4 Human Histamine A pKi 6.4 6.4 6.4 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.2 5.2 5.2 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.9 4.9 4.9 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.5 4.5 4.5 ChEMBL