U46619


SMILES CCCCC[C@@H](/C=C/[C@H]1[C@@H]2OC[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2)O
InChIKey LQANGKSBLPMBTJ-BRSNVKEHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 8XJO

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TP TA2R Human Prostanoid A pKd 7.8 7.8 7.8 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 7.5 7.5 7.5 Guide to Pharmacology
DP1 PD2R Human Prostanoid A pKi 5.4 5.65 5.9 Guide to Pharmacology
DP2 PD2R2 Human Prostanoid A pKi 5.5 5.5 5.5 Guide to Pharmacology
EP1 PE2R1 Human Prostanoid A pKi 4.5 4.5 4.5 Guide to Pharmacology
EP2 PE2R2 Human Prostanoid A pKi 4.9 4.9 4.9 Guide to Pharmacology
EP3 PE2R3 Human Prostanoid A pKi 4.9 4.9 4.9 Guide to Pharmacology
EP4 PE2R4 Human Prostanoid A pKi 5.7 5.7 5.7 Guide to Pharmacology
FP PF2R Human Prostanoid A pKi 6.6 6.6 6.6 Guide to Pharmacology
IP PI2R Human Prostanoid A pKi 4.2 4.2 4.2 Guide to Pharmacology
EP3 PE2R3 Rat Prostanoid A pKi 4.79 4.79 4.79 Guide to Pharmacology
EP1 PE2R1 Rat Prostanoid A pKi 5.2 5.2 5.2 Guide to Pharmacology
FP PF2R Mouse Prostanoid A pKi 6.0 6.0 6.0 Guide to Pharmacology
EP2 PE2R2 Rat Prostanoid A pKi 5.1 5.1 5.1 Guide to Pharmacology
EP4 PE2R4 Rat Prostanoid A pKi 5.6 5.6 5.6 Guide to Pharmacology
TP TA2R Human Prostanoid A pKi 8.26 8.26 8.26 ChEMBL
FP PF2R Mouse Prostanoid A pKi 6.0 6.0 6.0 PDSP Ki database
EP3 PE2R3 Bovine Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
FP PF2R Bovine Prostanoid A pKi 5.05 5.05 5.05 PDSP Ki database
TP TA2R Human Prostanoid A pKi 7.09 7.48 8.44 PDSP Ki database
EP1 PE2R1 Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
EP4 PE2R4 Human Prostanoid A pKi 5.0 5.35 5.7 PDSP Ki database
DP1 PD2R Human Prostanoid A pKi 5.4 5.4 5.4 PDSP Ki database
EP3 PE2R3 Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
FP PF2R Human Prostanoid A pKi 6.62 6.62 6.62 PDSP Ki database
IP PI2R Human Prostanoid A pKi 5.0 5.0 5.0 PDSP Ki database
TP TA2R Mouse Prostanoid A pKi 7.2 7.2 7.2 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Rat Prostanoid A pEC50 6.83 6.83 6.83 Guide to Pharmacology