CHEMBL141845


SMILES COc1ccccc1N1CCN(CCNC(=O)c2cnn3ccccc23)CC1
InChIKey XJGIQRQUJHWFSC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 9.17 9.17 9.17 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.24 6.24 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.54 6.71 7.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database