YM 218


SMILES O=C(N1CCC(CC1)N1CCCCC1)/C=C\1/c2ccccc2N(CCC1(F)F)C(=O)c1ccc(cc1)NC(=O)c1ccoc1C
InChIKey VDUUABBYYOPFAW-WMMMYUQOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 616.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1B V1BR Human Vasopressin and oxytocin A pKi 4.59 4.59 4.59 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 9.52 9.52 9.52 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 9.5 9.5 9.5 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 4.6 4.6 4.6 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 6.42 6.42 6.42 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 6.4 6.4 6.4 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKi 7.15 7.15 7.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database