SB-203580


SMILES C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1
InChIKey CDMGBJANTYXAIV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 377.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.59 5.59 5.59 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.47 5.47 5.47 ChEMBL
A1 AA1R Human Adenosine A pKi 5.76 5.76 5.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
glucagon GLR Human Glucagon B1 pIC50 7.43 7.43 7.43 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 4.97 4.97 4.97 ChEMBL
A2A AA2AR Human Adenosine A pIC50 5.22 5.22 5.22 ChEMBL
A1 AA1R Human Adenosine A pIC50 5.53 5.53 5.53 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL