AMIFOSTINE


SMILES NCCCNCCSP(=O)(O)O
InChIKey JKOQGQFVAUAYPM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 214.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.18 6.18 6.18 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.21 8.21 8.21 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 5.71 5.71 5.71 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 7.95 7.95 7.95 ChEMBL