CHEMBL104453
SMILES | c1ccc(CN2CCC(n3cccc3-c3cnco3)CC2)cc1 |
InChIKey | JTHXHSNJAJMWTQ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 4 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 307.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 5.0 | 5.0 | 5.0 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.2 | 7.2 | 7.2 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.11 | 6.11 | 6.11 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.21 | 6.36 | 6.5 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |