CHEMBL104692


SMILES CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccc([N+](=O)[O-])cc4)nc23)CC1
InChIKey JAYOKUDGYAUIEC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.57 6.57 6.57 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.11 8.11 8.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database