CHEMBL153067


SMILES c1ccc(C(CCc2nc(CCNCCc3ccccn3)c[nH]2)c2ccccc2)cc1
InChIKey WCRVDPZNPCPPJZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 410.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKd 7.98 7.98 7.98 ChEMBL
H1 HRH1 Guinea pig Histamine A pKd 8.36 8.36 8.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pEC50 6.28 6.28 6.28 ChEMBL
H1 HRH1 Guinea pig Histamine A pEC50 7.09 7.38 7.67 ChEMBL