CLADRIBINE


SMILES Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1
InChIKey PTOAARAWEBMLNO-KVQBGUIXSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 285.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 4.69 4.69 4.69 ChEMBL
A1 AA1R Rat Adenosine A pKi 5.13 5.13 5.13 ChEMBL
A2A AA2AR Rat Adenosine A pKi 8.33 8.33 8.33 Drug Central
A1 AA1R Rat Adenosine A pKi 8.29 8.29 8.29 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
RXFP1 RXFP1 Human Relaxin family peptide A Potency 4.65 4.72 4.8 ChEMBL