CHEMBL155866


SMILES Cc1cccc(C)c1OC(C)C1=NCCN1
InChIKey JWAAXMLRAVOKBQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 218.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.74 6.74 6.74 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.6 6.6 6.6 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.93 7.93 7.93 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.83 5.83 5.83 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.56 7.56 7.56 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.73 7.73 7.73 ChEMBL