CHEMBL156198


SMILES Fc1ccc(-c2cccc3c(CN4CCN(c5ccc(Cl)cc5)CC4)cnn23)cc1
InChIKey LAZCWDPLJFPPDI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 420.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.16 5.16 5.16 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.54 7.54 7.54 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.24 5.24 5.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.82 4.82 4.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database